Grape Seed Extract Targets and Kills Cancer Cells and Leaves Healthy Cells Unharmed
A study published this week in the journal Carcinogenesis shows that grape seed extract (GSE) kills squamous cell carcinoma cells, while leaving healthy cells unharmed.
Grape seed extracts are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid and polyphenols.
Human case reports and results from laboratory and animal studies provide preliminary evidence that grape seed extract may prevent heart diseases such as high blood pressure and high cholesterol. By limiting lipid oxdation, phenolics in grape seeds may reduce risk of heart disease, such as by inhibiting platelet aggregation and reducing inflammation.
It is estimated that 40 percent of American adults, or 50 million people, have metabolic syndrome. In a first human clinical trial, UC Davis cardiovascular researchers assessed the effect of grape seed extract on people with metabolic syndrome, a combination of risk factors that increase the risk for heart disease, including high blood pressure, excess abdominal body weight, high blood cholesterol fats and high blood sugar. They found that taking 300 milligrams of grape seed extract also had reduced serum oxidized LDL cholesterol levels.
Nearly 12,000 people will die of head and neck cancer in the United States this year and worldwide cases will exceed half a million.